NRL has a broad portfolio of technologies and over 1300 active patents or patent applications that are available for license. Below is a list of links to more information for a number of NRL technologies that have potential commercial applications.

Reactive and Catalytic Air Purification Materials

NRL has developed sorbents for the removal of toxic industrial gases such as ammonia and phosgene. The materials offer reactive and/or catalytic sites within a high surface area, hierarchical pore structure. The reactive/catalytic nature of the materials offers extended lifetimes to typical purification applications.

Cell and Biofactor Printable Biopapers

NRL has developed thin polymer/hydrogel scaffold sheets, or ‘biopapers’, which act as substrates for cell and biofactor printing. The patented NRL technique uses these biopapers as mechanically stable sheets to be used in a cell printing apparatus. Each polymer sheet can be addressed with different growth factors and then loaded into a cell printer for patterned cell seeding.

Dye and Drug Delivery with Phage-Like Nanoparticles

NRL has developed phage-like nanoparticles for the delivery of payloads to targeted eukaryotic cells. The nanoparticles are designed with reactive surface groups that can bind a dye, drug, antibody, etc. The modified nanoparticles can be used for cell tracking, cell imaging, and drug delivery. They are produced from E. coli as tailless T4 bacteriophage and modified to deliver content into targeted eukaryotic cells.

Self-Assembling, Reversible, Reagentless Biosensor

NRL has developed a reusable biosensor that easily targets analytes, like toxins or hormones, with a controllable binding affinity. The sensor can be reused for subsequent sensing events once it is washed of analyte. It can be easily adapted to target other analytes due to its modular design. The biosensor is self-assembled and consists of two co-functional entities. The first entity is a surface tethered biorecognition element, such as a receptor protein. The second entity is a multifunctional tethered modular arm that contains a point of surface attachment, a flexible DNA linker, and a dye label.

Self-Assembling, Biocompatible Quantum Dot Bioconjugates

NRL has developed self-assembling quantum dot-biological molecule conjugates. The quantum dot-biological molecule hybrid displays water solubility, biofunctionality, and bioelectroconductivity. The conjugation strategy is based on metal-affinity-driven interactions between the quantum dot's CdSe-ZnS core-shell and proteins or peptides appended with polyhistidine tags.

Catalytic Self-Decontaminating Materials

NRL has developed self-decontaminating structures based on porphyrin-embedded, target imprinted, porous, organosilicate sorbents. The materials rapidly sequester targets as a result of the affinity of the sorbent structures. Catalysis proceeds upon stimulation of the porphyrin moieties through illumination or by an applied current. This potential for dual stimulation provides the opportunity for utilization of the materials in sunlit or low light environments.

CoHex: Broad Spectrum Anti-Viral Compound

NRL is developing a hexamminecobalt(III) (CoHex) based anti-viral compound for both clinical and first responder use. Initial results with a variety of viruses (±ssRNA, -dsRNA, dsDNA, enveloped, non-enveloped) indicate that this compound is a very broad spectrum anti-viral agent.