Novel Sheath Flow Method
Click to view larger
Description:The Naval Research Laboratory (NRL) has developed a low cost, miniaturized, micro -fluidic approach to sheath flow systems used particularly in cytometery. The system utilizes a core stream and one or more sheath streams that are introduced into a single channel. The simple and straight-forward fabrication allows one or more grooves placed in the top and bottom of the channel, which directs the sheath fluid around the core stream, and separates the core stream from the walls of the channel. The patented NRL technique avoids the use of a nozzle or other constriction mechanism typically used, which can present issues with clogging. The sheath flow system completely surrounds the core stream, yet the fabrication of materials is simple and can be made from multiple materials. The system is reversible, which can be used to unsheathe the sheathed flow and recapture the core and sheath with high efficiency.
- Eliminates issues of clogging
- Ability to sheath high viscosity systems
- Fabricated in any material that can be machined or molded
- Efficient reversible system of sheathing and unsheathing
- Easily applied to liquid waveguides
- Biomedical Research
- Water Monitoring
- Bioterrorist Defense
- Food and Polymer Extrusion
- "Two simple and rugged designs for creating microfluidic sheath" Lab Chip, 8, 1097-1103 (2008).
- "Multi-wavelength microflow cytometer using groove-generated sheath flow" Lab Chip, 9, 1942-1950 (2009)
Click here for a more detailed PDF version of this technology.
Contact:Naval Research Laboratory
Technology Transfer Office, Code 1004