In 2009, the TIC/TIM Task Force released a document focused on toxic industrial chemicals and materials (TICs and TIMs) that pose a threat to the lungs and eyes of deployed troops. The list of compounds is prioritized based on toxic hazard and the likelihood of an encounter and includes compounds such as ammonia and cyanogen chloride as well as more commonly recognized threat agents. Traditional air purification materials employed by the military rely on porous carbons and functionalized versions of those materials. Our effort, directed at offering an alternative to carbon sorbents, seeks to utilize mesoporous organosilicas. The materials combine organic groups with inorganic silica components to produce sorbents with the properties of both. These porous sorbents form a high surface area scaffold into which functional moieties can be incorporated. Functional groups under consideration range from simple modifiers such as primary amine groups to complex macrocylic metal coordination sites.